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To correct for AIDS-related mortality, we needed the survival distribution, W t which we took to be a Weibull function with median of 9. Then, D t the probability per unit of time that people die t years after initial infection, was. Because deaths reduce prevalence, we added deaths from previous incident infections to our initial estimate of incidence, so that.

From equation 7 , we then obtained. Search ADS. Temporal changes in the rate of progression to death among Italians with known date of HIV seroconversion: estimates of the population effect of treatment. The cost effectiveness of combination antiretroviral therapy for HIV disease. Population-based hematologic and immunologic reference values for a healthy Ugandan population. Distribution of lymphocyte subsets in healthy human immunodeficiency virus-negative adult Ethiopians from two geographic locales. Acute sexually transmitted infections increase human immunodeficiency virus type 1 plasma viremia, increase plasma type 2 cytokines, and decrease CD4 cell counts.

Quantification of the variation due to laboratory and physiologic sources in CD4 lymphocyte counts of clinically stable HIV-infected individuals. Can highly-active antiretroviral therapy reduce the spread of HIV? Evaluation of the World Health Organization staging system for HIV infection and disease in Ethiopia: association between clinical stages and laboratory markers.

Reference values of CD4 T lymphocytes in human immunodeficiency virus-negative adult Nigerians.

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Determination of T-lymphocyte subsets on site in rural Tanzania: results in HIV-1 infected and non-infected individuals. Clinical signs and symptoms in the assessment of immunodeficiency in men with subtype C HIV infection in Harare, Zimbabwe.


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Evaluation of alternative CD4 technologies for the enumeration of CD4 lymphocytes. Absolute CD4 T-cell counting in resource-poor settings: direct volumetric measurements versus bead-based clinical flow cytometry instruments. Longitudinal human immunodeficiency virus type 1 load in the Italian seroconversion study: correlates and temporal trends of virus load. Within-subject variation in CD4 lymphocyte count in asymptomatic human immunodeficiency virus infection: implications for patient monitoring.

Patterns of T lymphocyte changes with human immunodeficiency virus infection: from seroconversion to the development of AIDS. Natural history of human immunodeficiency virus type 1 viremia after seroconversion and proximal to AIDS in a large cohort of homosexual men. Reference values for peripheral blood lymphocyte phenotypes applicable to the healthy adult population in Switzerland. HIV-1 infection in rural Africa: is there a difference in median time to AIDS and survival compared with that in industrialized countries?

Quality control in the flow cytometric measurement of T-lymphocyte subsets: the multicenter AIDS cohort study experience.

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Initiating highly active antiretroviral therapy in sub-Saharan Africa: an assessment of the revised World Health Organization scaling-up guidelines. Inter- and intrainstitutional evaluation of automated volumetric capillary cytometry for the quantitation of CD4- and CD8-positive T lymphocytes in the peripheral blood of persons infected with human immunodeficiency virus.

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CD4 lymphocyte enumeration in patients with human immunodeficiency virus infection using three-colour and four-colour dual-platform flow cytometry: an inter-laboratory comparative evaluation. Potential conflicts of interest: none reported. Issue Section:. Download all slides. View Metrics. Email alerts Article activity alert. Chidawanyika, K. Mutasa, E. Marinda, M. Mbizvo, J. Nthoo, P. Iliff, and J. Humphrey, unpublished data.

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We solved equation 3 iteratively, because the integrand depended only on the incidence at times preceding time t. Mortality followed directly from incidence and survival. We evaluated equation 10 numerically using Visual Basic in Excel version ; Microsoft. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account. Joongbu University. Sign In. Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation.


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  7. Volume Article Contents Abstract. Williams , Brian G. Oxford Academic. Google Scholar. Eline L. Eleanor Gouws. George P. Bertran Auvert. Christopher Dye. Cite Cite Brian G. Select Format Select format.


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